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The revised and up-to-date third edition of Drug Interactions in Infectious Diseases delivers a text that will enhance your clinical knowledge of the complex mechanisms, risks, and consequences of drug interactions associated with antimicrobials, infection, and inflammation.  The third edition features five new chapters that cover material not addressed in previous editions.  These new chapters describe interactions with a number of drug classes such as non-HIV antiviral, antimalarial, antiparasitic, antihelmintic,  macrolide, azalide and ketolide agents.  A novel chapter on probe cocktail studies has been included to highlight an important research tool for drug development.  These chapters address material that cannot be retrieved easily in the medical literature.  The highly acclaimed food-drug interactions as well as the study design and analysis chapters remain definitive references.  The newly written drug-cytokine interaction highlights the need for our improved understanding of the complex interrelationship of acute infection, inflammation, and the risk of drug interactions.  Informative tables on specific drug-drug interactions are provided throughout the chapters as a quick clinical resource. The Third Edition of Drug Interactions in Infectious Diseases is a distillation of relevant drug interactions associated with antimicrobials, infection, and inflammation.  This concise review of the mechanisms and strategies to manage drug interactions should be valuable to all health care practitioners. Features ·         Definitive reference source of up-to-date information on antimicrobial drug interactions ·         Informative tables on the degree of interaction for specific antimicrobial agents ·         In-depth discussion of mechanisms and potential mechanistic pathways of interaction ·         New chapters on non-HIV antiviral, antimalarial, antiparasitic, and macrolide, azalide and ketolide agents ·         New chapter on probe-cocktail studies as a research tool to study drug-drug interactions ·         Inclusion of new antimicrobial agents and their associated drug interactions ·         First rate chapters on study design and analysis, and drug-food interactions ·         A fresh perspective on drug-cytokine interactions ·         Authoritative chapter on regulatory considerationsof drug interactions during drug development ·         Inclusion of new antimicrobial agents and their associated drug interactions.

Anti-infective agents -- Side effects. --- Drug interactions. --- Anti-infective agents --- Drug interactions --- Pharmacological Processes --- Therapeutic Uses --- Physiological Processes --- Pharmacological Phenomena --- Pharmacologic Actions --- Chemical Actions and Uses --- Physiological Phenomena --- Chemicals and Drugs --- Phenomena and Processes --- Anti-Infective Agents --- Drug Interactions --- Health & Biological Sciences --- Medicine --- Pharmacy, Therapeutics, & Pharmacology --- Infectious Diseases --- Side effects --- Side effects. --- Interactions, Drug --- Pharmacy. --- Medicine. --- Pharmaceutical technology. --- Infectious diseases. --- Medicine & Public Health. --- Infectious Diseases. --- Pharmaceutical Sciences/Technology. --- Drugs --- Emerging infectious diseases. --- Chemistry --- Materia medica --- Pharmacology --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Pharmaceutical laboratory techniques --- Pharmaceutical laboratory technology --- Technology, Pharmaceutical --- Technology

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The 4th edition of Drug Interactions in Infectious Diseases is being split into two separate volumes – “Mechanisms and Models of Drug Interactions” and “Antimicrobial Drug Interactions”. This volume, “Mechanisms and Models of Drug Interactions,” delivers a text that enhances clinical knowledge of the complex mechanisms, risks, and consequences of drug interactions associated with antimicrobials, infection, and inflammation. The book provides a comprehensive review of basic clinical pharmacology with a focus on metabolism and transporter-mediated drug interactions. The chapters address materials that cannot be retrieved easily in the medical literature, including materials focused on the complex interrelationship of acute infection, inflammation, and the risk of drug interactions in the Drug-Cytokine chapter. The Food-Drug and Herb-Drug interactions chapters remain definitive resources. A new chapter on in vitro modeling of drug interactions is included along with updates on design and data analysis of clinical drug interaction studies. Authoritative discussion of models for regulatory decision-making on drug-drug interactions provides the necessary framework to aid antimicrobial drug development. This concise review of the mechanisms and models of drug interactions provides important insights to health care practitioners as well as scientists in drug development.

Drug interactions. --- Communicable diseases. --- Medicine. --- Pharmacy. --- Pharmaceutical technology. --- Infectious diseases. --- Biomedicine. --- Pharmaceutical Sciences/Technology. --- Infectious Diseases. --- Pharmaceutical laboratory techniques --- Pharmaceutical laboratory technology --- Technology, Pharmaceutical --- Technology --- Chemistry --- Medicine --- Drugs --- Materia medica --- Pharmacology --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Contagion and contagious diseases --- Contagious diseases --- Infectious diseases --- Microbial diseases in human beings --- Zymotic diseases --- Diseases --- Infection --- Epidemics --- Interactions, Drug --- Side effects --- Emerging infectious diseases. --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases

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• Reference Manager
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The revised and up-to-date third edition of Drug Interactions in Infectious Diseases delivers a text that will enhance your clinical knowledge of the complex mechanisms, risks, and consequences of drug interactions associated with antimicrobials, infection, and inflammation.  The third edition features five new chapters that cover material not addressed in previous editions.  These new chapters describe interactions with a number of drug classes such as non-HIV antiviral, antimalarial, antiparasitic, antihelmintic,  macrolide, azalide and ketolide agents.  A novel chapter on probe cocktail studies has been included to highlight an important research tool for drug development.  These chapters address material that cannot be retrieved easily in the medical literature.  The highly acclaimed food-drug interactions as well as the study design and analysis chapters remain definitive references.  The newly written drug-cytokine interaction highlights the need for our improved understanding of the complex interrelationship of acute infection, inflammation, and the risk of drug interactions.  Informative tables on specific drug-drug interactions are provided throughout the chapters as a quick clinical resource. The Third Edition of Drug Interactions in Infectious Diseases is a distillation of relevant drug interactions associated with antimicrobials, infection, and inflammation.  This concise review of the mechanisms and strategies to manage drug interactions should be valuable to all health care practitioners. Features ·         Definitive reference source of up-to-date information on antimicrobial drug interactions ·         Informative tables on the degree of interaction for specific antimicrobial agents ·         In-depth discussion of mechanisms and potential mechanistic pathways of interaction ·         New chapters on non-HIV antiviral, antimalarial, antiparasitic, and macrolide, azalide and ketolide agents ·         New chapter on probe-cocktail studies as a research tool to study drug-drug interactions ·         Inclusion of new antimicrobial agents and their associated drug interactions ·         First rate chapters on study design and analysis, and drug-food interactions ·         A fresh perspective on drug-cytokine interactions ·         Authoritative chapter on regulatory considerationsof drug interactions during drug development ·         Inclusion of new antimicrobial agents and their associated drug interactions

Pharmacology. Therapy --- Infectious diseases. Communicable diseases --- farmacologie --- besmettelijke ziekten

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The 4th edition of Drug Interactions in Infectious Diseases is being split into two separate volumes – “Mechanisms and Models of Drug Interactions” and “Antimicrobial Drug Interactions”. This volume, “Antimicrobial Drug Interactions,” delivers a quick clinical resource that distills relevant drug interactions by antimicrobial drug class. The book provides informative tables on specific drug-drug interactions that include the degree and severity of the expected interaction. A mechanistic basis for drug-drug interactions is also provided to link observed interactions to pharmacologic characteristics of key drug classes. This complete resource is organized by major antibacterial, antimycobacterial, antiviral, antifungal, antimalarial, and antiprotozoal class. In line with current innovations in antimicrobial drug development, a distinct chapter on the pharmacologic management of drug interactions in hepatitis B virus (HBV) and hepatitis C virus (HCV)-related infections is included. Two new chapters are dedicated to the management of human immunodeficiency virus (HIV) drug-drug interactions given the breadth of antiretroviral class-specific effects. This comprehensive review of known drug interactions and strategies to manage them is an invaluable resource to all health care practitioners.

Pharmacology. Therapy --- Infectious diseases. Communicable diseases --- farmacologie --- besmettelijke ziekten